Big Pharma had a plan.

It designed a trial for a COX-2 drug and it ran.

Yet it wasn’t enough to get pain low.

What’s this?

We’re still here in the land of no?

Fiddle with the randomizing, a doctor said.

The drug’s not to blame.

All clinical trials simply are not the same.

When comparing just the right subjects in a test,

you’ll clearly get an effect that’s the best.

Would you like to try it?

Why, yes. Yes, we would.

Big Pharma took the bait. Since Big Pharma re-powered the trial,

Its COX-2 CV effects were much less.

With deception and guile,

It’s the land of success.

Reset your trial parameters and you just might declare,

I’m a blockbuster success.

Now you’re getting somewhere.